The Mother-Daughter Initiative (MDI) is a research collaboration by Jhpiego - affiliate of Johns Hopkins University with the Philippines and Thailand that test the feasibility and acceptability of a strategy to deliver comprehensive cervical cancer prevention services by integrating the HPV vaccine for girls ages 9-13 into already successful screening and treatment programs for mothers.

In the Philippines, the goal was to:

1) vaccinate 50% of 9-13-year-old girls in 3 established CECAP sites namely Los Banos, Laguna; Minglanilla, Cebu; and Pagbilao, Quezon;

2) Assess the mothers' acceptability of their daughter receiving all 3 doses after the mothers are screened or treated for cervical pre-cancer; and

3) Share the information and experiences from this research that would encourage women to bring their daughters for vaccination while undergoing cancer screening.

The study started in September 2010, and finalized in November 2012.

 

MDI Sites

Dose 1

Dose 2

Dose 3

LB

1333

1301

1278

MN

1334

1334

1334

PB

1333

1212

912

TOTAL

100.0% (4000)

96.18% (3847)

88.1% (3524)

 

MDI Indicators

LB

MN

PB

Total

No. of Women screened for cervical cancer

3867

1747

1696

7310

No of women treated for pre cancerous lesion

10

5

5 

20

No. of participants during CECAP promotion activities

13674

1858

2441

17973

Over the duration of the MDI project, the challenges faced were 1) the existence of myths and misconceptions (such as rumours that HPV vaccines were an abortifacient and could cause infertilitycausing hesitation on the part of potential participants;  2) the securing of consent from legal guardians especially when the parents were not present; 3) the coinciding HPV vaccination and school schedules; 4) the heavy workload of providers; 5) the accessibility for girls in geographically isolated areas; 6) severe weather conditions; and 7) adverse events or pregnancy cases.

However, despite the challenges, the MDI implementation phase in the Philippines was satisfactorily completed; 4,000 young girls received HPV vaccines. With 88% of the girls that received the first dose also completing the full three dose schedule; 300 HPV Knowledge and Intention Interview and 400 Post Dose HPV Vaccine Interview were conducted and completed; 17,973 individuals participated in CECAP awareness campaign activities; and 7,310 women aged 25-45 went for cervical cancer screening and 20 received treatment for precancerous lesion.